Sunday, 31 March 2019
from Times of India https://timesofindia.indiatimes.com/business/india-business/starting-today-new-rules-of-saving-spending-and-investing-kick-in/articleshow/68664895.cms
Starting today, new investing rules kick in
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/with-dew-we-knew-batting-would-get-easier-says-ms-dhoni-after-match-winning-effort/articleshow/68665365.cms
With dew, we knew batting would get easier: Dhoni
from Times of India https://timesofindia.indiatimes.com/business/india-business/buyer-cant-wait-indefinitely-for-flat-says-supreme-court-on-7-year-delay/articleshow/68662461.cms
Buyer can't wait indefinitely for flat: SC
from Times of India https://timesofindia.indiatimes.com/india/isros-pslv-c45-places-drdo-intelligence-satellite-emisat-in-orbit-mission-continues/articleshow/68664357.cms
PSLV-C45 places DRDO intelligence satellite Emisat in orbit
from Times of India https://timesofindia.indiatimes.com/india/pslv-c45-launch-live-updates/articleshow/68663156.cms
Live updates: ISRO to launch Emisat, 28 foreign satellites shortly
from Times of India https://timesofindia.indiatimes.com/india/buyer-cant-wait-indefinitely-for-flat-says-supreme-court-on-7-year-delay/articleshow/68662461.cms
Buyer can't wait indefinitely for flat: SC
from Times of India https://timesofindia.indiatimes.com/india/timestopten.cms
TOI Top 10: Fight that could change India’s banks
from Times of India https://timesofindia.indiatimes.com/elections/lok-sabha-elections-2019/uttar-pradesh/news/were-working-with-a-74-plus-seat-target-in-up-yogi-adityanath/articleshow/68662803.cms
Working with a 74-plus seat target in UP: Yogi
from Times of India https://timesofindia.indiatimes.com/india/took-game-to-site-from-where-terror-remote-controlled-pm-modi/articleshow/68662521.cms
Took 'game' to site from where terror emanates: PM
from Times of India https://timesofindia.indiatimes.com/elections/news/weve-proved-that-an-honest-central-government-can-run-india-arun-jaitley/articleshow/68661968.cms
'We proved an honest central govt can run India'
from Times of India https://timesofindia.indiatimes.com/elections/lok-sabha-elections-2019/kerala/news/rahul-gandhi-makes-a-southern-outreach-via-wayanad/articleshow/68661482.cms
Rahul makes a 'southern outreach' via Wayanad
from Times of India https://timesofindia.indiatimes.com/india/banihal-attacker-had-suicide-note-but-abandoned-car/articleshow/68662498.cms
Banihal attacker had suicide note, but 'left' car
from Times of India https://timesofindia.indiatimes.com/india/indian-students-enrolling-in-australia-surged-25-in-2018/articleshow/68662108.cms
Indian students enrolling in Oz surged 25% in '18
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/ipl-2019-ms-dhonis-intelligent-batting-in-tough-conditions-scripts-csks-third-win-on-the-trot/articleshow/68661755.cms
IPL: Dhoni scripts CSK's third win on the trot
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/youngest-ipl-debutant-prayas-barman-managing-rcb-and-cbse-tests-at-same-time/articleshow/68660918.cms
IPL debutant Barman managing RCB and CBSE tests
from Times of India https://timesofindia.indiatimes.com/world/uk/uk-tax-fraud-funded-al-qaida-in-pakistan-afghanistan-report/articleshow/68660251.cms
UK's multi-million tax fraud funded terror networks in Pakistan: Report
from Times of India https://timesofindia.indiatimes.com/india/rahuls-decision-to-pick-wayanad-draws-sharp-reactions-from-left-right/articleshow/68659792.cms
Rahul's move to pick Wayanad draws sharp reactions from Left, Right
from Times of India https://timesofindia.indiatimes.com/india/vijay-mallya-attacks-bjp-says-his-poster-boy-assertion-vindicated/articleshow/68652312.cms
Fully vindicated by PM Modi's statement: Mallya
from Times of India https://timesofindia.indiatimes.com/elections/news/will-request-bjps-sister-organisations-not-to-support-modi-shah-mamata/articleshow/68659446.cms
'Will urge BJP's sister concerns not to back Modi'
from Times of India https://timesofindia.indiatimes.com/india/govt-extends-deadline-for-linking-pan-with-aadhaar-till-september-30/articleshow/68658846.cms
PAN-Aadhaar linking deadline extended to Sept 30
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/csk-vs-rr-ipl-2019-live-score-rajasthan-royals-opt-to-field-against-chennai-super-kings/articleshow/68658103.cms
CSK vs RR Live: RR opt to field against CSK
from Times of India https://timesofindia.indiatimes.com/india/pakistan-in-a-fix-after-balakot-strikes-pm-modi/articleshow/68657879.cms
Pakistan in a fix after Balakot strikes: PM Modi
from Times of India https://timesofindia.indiatimes.com/india/tried-my-best-to-protect-nations-wealth-from-corrupt-pm-narendra-modi/articleshow/68656974.cms
Nation wants 'chowkidar', not raja-maharajas: PM
from Times of India https://timesofindia.indiatimes.com/sports/badminton/live-2019-india-open-badminton-final-live-kidambi-srikanth-final-viktor-axelsen/articleshow/68655334.cms
Indian Open Final Live: Srikanth vs Axelsen
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/srh-vs-rcb-ipl-live-score-streaming-updates-match-11-hyderabad/articleshow/68654610.cms
IPL Live Updates: RCB opt to bowl vs SRH
from Times of India https://timesofindia.indiatimes.com/india/court-martial-of-major-gogoi-completed-may-face-reduction-of-seniority/articleshow/68656165.cms
Major Gogoi may face reduction of seniority
from Times of India https://timesofindia.indiatimes.com/elections/news/joining-congress-as-it-is-national-party-in-true-sense-lalu-advised-to-do-so-shatrughan/articleshow/68655942.cms
Lalu advised me to join Congress: Shatrughan
from Times of India https://timesofindia.indiatimes.com/india/rahul-gandhis-contest-from-wayanad-a-fight-against-left-kerala-cm/articleshow/68655705.cms
Rahul fighting against Left not BJP: Kerala CM
from Times of India https://timesofindia.indiatimes.com/elections/news/rahul-gandhi-fled-to-kerala-as-he-fears-amethi-will-seek-account-of-work-amit-shah/articleshow/68655517.cms
Worried Rahul fled Amethi: Amit Shah
from Times of India https://timesofindia.indiatimes.com/elections/news/wayanad-is-a-safe-bet-for-rahul-gandhi/articleshow/68655441.cms
Wayanad is a safe bet for Rahul Gandhi
from Times of India https://timesofindia.indiatimes.com/india/mig-27-aircraft-crashes-near-jodhpur-in-rajasthan/articleshow/68654562.cms
MiG 27 aircraft crashes near Jodhpur in Raj
from Times of India https://timesofindia.indiatimes.com/india/kerala-cm-says-rahul-fighting-against-left-not-bjp-vows-to-defeat-him/articleshow/68654371.cms
Rahul fighting against Left not BJP: Kerala CM
Saturday, 30 March 2019
from Times of India https://timesofindia.indiatimes.com/home/sunday-times/now-police-use-apps-to-catch-a-criminal/articleshow/68649118.cms
Now, police use apps to catch a criminal
from Times of India https://timesofindia.indiatimes.com/elections/news/lok-sabha-elections-rahul-gandhi-to-contest-from-wayanad-in-kerala/articleshow/68653530.cms
Lok Sabha polls: Rahul to contest second seat from Wayanad in Kerala
from Times of India https://timesofindia.indiatimes.com/elections/lok-sabha-election-rahul-gandhi-rally-andhra-modi-bjp-2019-march-31/articleshow/68651893.cms
Live: Rahul to contest from Wayanad
from Times of India https://timesofindia.indiatimes.com/rs-1-crore-foreign-trip-vote-linked-bonus-for-tamil-nadu-party-cadre/articleshow/68651546.cms
Rs 1 crore: Vote-linked bonus for TN party cadre
from Times of India https://timesofindia.indiatimes.com/sports/more-sports/shooting/i-hope-we-get-an-individual-gold-in-tokyo-abhinav-bindra/articleshow/68652479.cms
I hope we get an individual gold in Tokyo: Bindra
from Times of India https://timesofindia.indiatimes.com/world/us/investigator-says-amazon-chiefs-phone-hacked-by-saudis/articleshow/68652066.cms
'Saudis hacked Amazon CEO Jeff Bezos' phone'
from Times of India https://timesofindia.indiatimes.com/india/holiday-inn-linked-to-laundering-attached/articleshow/68650999.cms
Holiday Inn linked to money laundering, attached
from Times of India https://timesofindia.indiatimes.com/elections/lok-sabha-elections-2019/tamil-nadu/news/rs-1-crore-foreign-trip-vote-linked-bonus-for-tamil-nadu-party-cadre/articleshow/68651546.cms
Rs 1 crore: Vote-linked bonus for TN party cadre
from Times of India https://timesofindia.indiatimes.com/business/india-business/jet-to-pay-pilots-december-salary-will-wait-for-funds-to-clear-arrears/articleshow/68651087.cms
Jet Airways to pay pilots December salary
from Times of India https://timesofindia.indiatimes.com/nri/other-news/karnataka-techie-murdered-in-germany/articleshow/68651030.cms
Karnataka techie murdered in Germany
from Times of India https://timesofindia.indiatimes.com/india/red-herring-pakistan-wants-details-of-pulwama-bombers-guns/articleshow/68650490.cms
Red herring? Pakistan wants details of Pulwama bomber's guns
from Times of India https://timesofindia.indiatimes.com/elections/lok-sabha-elections-2019/gujarat/news/allies-attest-to-amit-shahs-stature-as-no-2-in-coalition/articleshow/68650847.cms
Allies attest to Shah's stature as no. 2 in coalition
from Times of India https://timesofindia.indiatimes.com/elections/news/do-seats-belong-to-the-party-or-families-asks-pm-modi/articleshow/68650882.cms
Do seats 'belong' to the party or families, asks PM
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/ipl-2019-delhi-capitals-beat-kolkata-knight-riders-in-super-over-after-prithvi-shaw-heroics/articleshow/68650821.cms
DC beat KKR in Super Over after Shaw heroics
from Times of India https://timesofindia.indiatimes.com/india/javadekar-hits-out-at-p-c-chacko-for-calling-gandhi-family-indias-first-family/articleshow/68648990.cms
BJP slams P C Chacko's 'first family' remark
from Times of India https://timesofindia.indiatimes.com/india/indias-satellite-destroying-missile-sends-message-to-china-pakistan/articleshow/68647653.cms
Stark message to China, Pak: India's A-Sat changes strategic calculus
from Times of India https://timesofindia.indiatimes.com/business/india-business/nirav-modis-defence-team-even-uses-his-pet-dog-in-attempt-to-win-bail/articleshow/68637926.cms
Pet dog, £1 million security: Nirav's team pulled out all stops to win bail
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/ipl-2019-kl-rahul-anchors-kings-xi-punjab-to-eight-wicket-win-over-mumbai-indians/articleshow/68647860.cms
IPL: KL Rahul anchors Kings XI to 8-wicket win
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/dc-vs-kkr-ipl-live-score-streaming-updates-match-10-delhi/articleshow/68646943.cms
DC vs KKR: Delhi Capitals opt to field vs KKR
from Times of India https://timesofindia.indiatimes.com/business/india-business/as-strike-threat-looms-jet-airways-promises-to-pay-december-salary-to-pilots-engineers/articleshow/68647380.cms
Jet promises to pay December salary to pilots
from Times of India https://timesofindia.indiatimes.com/world/middle-east/iran-looks-to-remote-port-to-beat-us-sanctions/articleshow/68646571.cms
Iran looks to remote India-operated port to beat US sanctions
from Times of India https://timesofindia.indiatimes.com/india/if-special-status-withdrawn-relationship-between-jk-and-union-of-india-will-be-over-mehbooba/articleshow/68646894.cms
No ties with J&K if Art 370 revoked: Mufti to govt
from Times of India https://timesofindia.indiatimes.com/world/us/with-a-piece-of-paper-trump-called-on-kim-to-hand-over-nuclear-weapons/articleshow/68646165.cms
With a piece of paper, Trump called on Kim to hand over nuclear weapons
from Times of India https://timesofindia.indiatimes.com/elections/news/lok-sabha-polls-will-be-fought-on-issue-of-who-will-lead-country-amit-shah/articleshow/68643415.cms
People saw in Modi the leader they waited for 70 years: Amit Shah
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/kxip-vs-mi-ipl-2019-live-score-mumbai-indians-lose-rohit-suryakumar-quickly/articleshow/68643881.cms
KXIP vs MI Live: Shami strikes to dismiss De Kock
from Times of India https://timesofindia.indiatimes.com/elections/news/there-were-issues-between-shiv-sena-and-bjp-but-resolved-now-uddhav-thackeray/articleshow/68645231.cms
All issues resolved: Uddhav on Sena, BJP ties
from Times of India https://timesofindia.indiatimes.com/india/isro-finally-opens-door-for-people-to-watch-rocket-launches/articleshow/68644933.cms
Now, watch rocket launches from Isro's gallery
from Times of India https://timesofindia.indiatimes.com/elections/news/shashi-tharoors-squeamish-tweet-kicks-of-controversy/articleshow/68644731.cms
Tharoor's 'squeamish' tweet triggers controversy
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/kxip-vs-mi-ipl-live-score-streaming-updates-match-9-mohali/articleshow/68643881.cms
KXIP vs MI Live: KXIP win toss, opt to bowl vs MI
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/ipl-2019-kxip-vs-mi-preview-mumbai-indians-look-to-revel-in-kings-xi-punjabs-court/articleshow/68640958.cms
IPL 2019: MI look to revel in KXIP's court
from Times of India https://timesofindia.indiatimes.com/city/chennai/a-crime-of-passion-with-few-parallels/articleshow/68638642.cms
Life term for Saravana owner: Final closure for a crime of passion
from Times of India https://timesofindia.indiatimes.com/elections/lok-sabha-elections-2019/gujarat/news/amit-shah-files-nomination-papers-for-gandhinagar-lok-sabha-seat/articleshow/68643001.cms
Amit Shah files nomination from Gandhinagar
from Times of India https://timesofindia.indiatimes.com/india/jk-car-blast-on-jammu-srinagar-highway-near-banihal/articleshow/68642731.cms
Blast in car near CRPF convoy in Jammu
from Times of India https://timesofindia.indiatimes.com/business/india-business/income-tax-gst-offices-to-remain-open-on-march-30-31-to-facilitate-year-end-collection/articleshow/68643459.cms
I-T, GST offices to remain open on Mar 30, 31
from Times of India https://timesofindia.indiatimes.com/india/india-has-3-times-more-schools-than-china-but-they-are-a-mess/articleshow/68616961.cms
India beats China in schools but lags in education
from Times of India https://timesofindia.indiatimes.com/india/indian-national-stabbed-to-death-in-munich/articleshow/68642726.cms
Indian national stabbed to death in Munich
Friday, 29 March 2019
from Times of India https://timesofindia.indiatimes.com/india/breaking-news-live-updates-march-30/articleshow/68640833.cms
Live: Car explosion in J&K's Banihal
from Times of India https://timesofindia.indiatimes.com/india/why-us-is-rushing-to-return-to-the-moon/articleshow/68641359.cms
Why US is rushing to return to the moon
from Times of India https://timesofindia.indiatimes.com/elections/modi-rally-west-bengal-rahul-gandhi-congress-elections-lok-sabha-2019-march-30/articleshow/68640179.cms
Live: Top NDA leaders at Shah's nomination filing
from Times of India https://timesofindia.indiatimes.com/home/science/why-this-71-year-old-has-never-felt-pain-in-life/articleshow/68640266.cms
Why this 71-year-old has never felt pain in life
from Times of India https://timesofindia.indiatimes.com/home/science/us-tracking-250-270-objects-from-indian-asat-test-debris-iss-not-at-risk-pentagon/articleshow/68640824.cms
US tracking Indian ASAT test debris: Pentagon
from Times of India https://timesofindia.indiatimes.com/elections/lok-sabha-elections-2019/west-bengal/news/why-bjp-is-eyeing-a-breach-in-didis-bengal-fortress/articleshow/68639882.cms
Why BJP is eyeing a breach in Didi’s Bengal turf
from Times of India https://timesofindia.indiatimes.com/world/uk/nirav-modi-was-trying-for-vanuatu-citizenship-uk-judge/articleshow/68638770.cms
Nirav Modi was trying for Vanuatu citizenship: UK judge
from Times of India https://timesofindia.indiatimes.com/india/india-us-seek-meaningful-and-irreversible-action-from-pakistan-on-terror/articleshow/68639768.cms
India, US seek meaningful action from Pak on terror
from Times of India https://timesofindia.indiatimes.com/elections/news/congress-first-family-wont-be-back-in-power-pm-modi/articleshow/68639271.cms
Congress first family won't be back in power: Modi
from Times of India https://timesofindia.indiatimes.com/india/oxfam-flags-gender-pay-gap-lack-of-quality-jobs-in-india/articleshow/68639282.cms
Oxfam flags gender pay gap in India
from Times of India https://timesofindia.indiatimes.com/world/uk/london-court-agrees-nirav-modi-is-flight-risk-rejects-bail-again/articleshow/68638610.cms
UK court agrees Nirav is flight risk, rejects bail
from Times of India https://timesofindia.indiatimes.com/business/india-business/jet-pilots-may-go-on-strike-from-april-1-as-no-word-yet-on-payment-of-salary-dues/articleshow/68637356.cms
Unpaid, Jet pilots to go on strike from April 1
from Times of India https://timesofindia.indiatimes.com/india/counting-50-of-paper-trail-will-delay-results-by-5-days-ec/articleshow/68638915.cms
Counting 50% of paper trail will delay results: EC
from Times of India https://timesofindia.indiatimes.com/elections/news/rahul-gandhi-hints-he-may-fight-from-two-lok-sabha-seats/articleshow/68638991.cms
Rahul hints he may fight from two Lok Sabha seats
from Times of India https://timesofindia.indiatimes.com/business/india-business/nirav-modi-and-vijay-mallya-to-share-same-jail-cell-in-mumbai/articleshow/68636947.cms
May share cell with Mallya, says UK judge in lighter vein at Nirav hearing
from Times of India https://timesofindia.indiatimes.com/elections/news/pm-modis-mission-shakti-address-didnt-violate-model-code-of-conduct-ec/articleshow/68636676.cms
PM's address didn't violate code of conduct: EC
from Times of India https://timesofindia.indiatimes.com/elections/news/will-scrap-niti-aayog-if-congress-voted-to-power-rahul-gandhi/articleshow/68636135.cms
Cong will scrap Niti Aayog if voted to power: Rahul
from Times of India https://timesofindia.indiatimes.com/business/india-business/pnb-scam-nirav-modi-to-remain-in-jail-as-uk-court-rejects-bail-plea/articleshow/68635555.cms
PNB scam: Nirav Modi to remain in jail as UK court rejects bail plea
from Times of India https://timesofindia.indiatimes.com/india/can-chinese-muslims-help-india-corner-jem-terrorist-masood-azhar/articleshow/68634400.cms
Can Chinese Muslims help India corner JeM terrorist Masood Azhar?
from Times of India https://timesofindia.indiatimes.com/business/india-business/nirav-modi-made-death-threats-to-witnesses-uk-court-told/articleshow/68635079.cms
Nirav made death threats to witnesses, court told
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/srh-vs-rr-ipl-live-score-streaming-updates-match-8-hyderabad/articleshow/68633968.cms
SRH vs RR: Rajasthan opt to bat against SRH
from Times of India https://timesofindia.indiatimes.com/sports/badminton/kidambi-srikanth-parupalli-kashyap-seal-semifinal-spots-at-india-open/articleshow/68633829.cms
Srikanth, Kashyap enter semifinals at India Open
from Times of India https://timesofindia.indiatimes.com/elections/news/rahul-gandhi-does-not-rule-out-contesting-from-second-seat-says-party-will-take-a-call/articleshow/68633652.cms
Rahul: It is up to Priyanka to decide if she wants to fight LS polls or not
from Times of India https://timesofindia.indiatimes.com/india/breaking-news-live-march-29/articleshow/68623831.cms
Live: Nirav Modi's bail plea hearing underway
from Times of India https://timesofindia.indiatimes.com/elections/news/hardik-patels-poll-hopes-diminish-as-hc-refuses-to-stay-conviction/articleshow/68632519.cms
Blow to Hardik: HC rejects plea to stay conviction
from Times of India https://timesofindia.indiatimes.com/sports/cricket/ipl/top-stories/call-for-no-ball-tech-as-virat-kohli-slams-ridiculous-ipl-error/articleshow/68631580.cms
Call for no-ball technology as Virat Kohli slams 'ridiculous' IPL error
from Times of India https://timesofindia.indiatimes.com/elections/lok-sabha-elections-2019/maharashtra/news/mumbai-north-another-election-another-bollywood-figure/articleshow/68631381.cms
Mumbai: Another poll, another Bollywood figure
from Times of India https://timesofindia.indiatimes.com/sports/cricket/news/turbanator-harbhajan-recalls-indias-historic-victory-against-australia/articleshow/68625348.cms
'Turbanator' recalls match that changed his life
When Paul Manafort appeared in court for sentencing recently, he was in a wheelchair and pleaded for leniency, in part because “his confinement had taken a toll on his physical and mental health.” He reportedly had symptoms of depression and anxiety — but what was the health problem that put him in a wheelchair? According to multiple news reports, the answer is gout. Yes, that ancient disease you may have thought didn’t exist anymore has stricken Mr. Manafort. He joins the rising number of people in the country diagnosed with this common disease.
What is gout?
Gout is a cause of severe joint pain and inflammation. This form of arthritis develops when crystals of uric acid (a normal byproduct of our body’s metabolism) deposit near joints and other parts of the body. Gout develops because the body makes too much uric acid, the kidneys don’t get rid of enough of it, or a combination of both.
For some, dietary factors — consuming foods and beverages that produce a lot of uric acid — seem to play an important role. For others, the problem may be one or more medications that cause the level of uric acid to rise. Genetic factors are also important; the way the body handles uric acid may vary based on the genes you inherit. The observation that gout sometimes runs in families supports a genetic contribution.
Some facts about gout
Gout is on the rise. According to the most recent estimates, nearly 4% of the adult population in US now has gout, while less than 3% had it 25 years ago. The increase is thought to be due to rising rates of obesity, use of certain medications, and the rising popularity of high-fructose corn syrup (as found in carbonated beverages and many other foods and drinks).
Men are more likely to get gout and can develop gout at any age, but women rarely get it before menopause.
Gout used to be called “The disease of kings.” This was supposedly because in ancient times, only those who were wealthy enough to consume a lot of alcohol, red meat, and organ meats (such as liver) tended to get gout. While Henry VIII reportedly had gout, it can no longer be considered the disease of kings. People of any socioeconomic status can have gout.
Diet may matter less than we thought. A new study analyzed dietary surveys, genetic analyses, and uric acid levels among more than 16,000 people in the US. They found that dietary choices accounted for less than 0.5% of the variation in uric acid, while genetic factors accounted for about 24%. Since gout is caused by high uric acid, this study suggests that genetics matter much more than diet when it comes to the risk of gout.
The good news
Among all forms of arthritis, gout is among the most preventable and treatable. Some of the best ways to avoid gout include maintaining a healthy weight, moderating alcohol consumption, and maintaining a healthy blood pressure.
And there are highly effective treatments. These include several medications (including corticosteroids, anti-inflammatory medications, and colchicine) to treat a sudden gout attack, and others (including allopurinol and febuxostat) that can prevent future attacks by lowering uric acid. In fact, treatments for gout are so good, it’s quite unusual that a person would be confined to a wheelchair despite proper treatment.
There may be more to gout than arthritis
While the sudden and severe arthritis of gout gets most of the attention, high blood uric acid may cause other problems. A kidney stone is another common (and terribly painful) complication. In addition, there is mounting evidence that high uric acid may contribute to high blood pressure, kidney disease, and cardiovascular disease, and that medications to lower uric acid may reduce the risk of these problems (although more research is needed to prove this).
The bottom line
Although gout can be temporarily debilitating, excellent treatments are available. So, while most of the news hasn’t been good for Paul Manafort lately, his gout should be just a temporary setback.
The post Why the wheelchair? Could it be gout? appeared first on Harvard Health Blog.
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Why the wheelchair? Could it be gout?
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Motorists get relief again, 3rd party insurance cover won’t be hiked
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China's OBOR has nat'l security element: Pompeo
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Pak still counting bodies: PM takes jibe at oppn
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After ASAT, where do India and China stand on space race
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Govt took steps to set up 'chowkidar' in space: PM
from Times of India Lok Sabha elections 2019 Govt has taken measures to set up 'chowkidar' in space: PM Modi in Odisha
Govt took steps to set up chowkidar in space: PM
Thursday, 28 March 2019
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LS polls: Key to Delhi could lie in eastern UP
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Lok Sabha elections: How BJP beats Congress in turning votes into seats
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'Serial offender': India slams Pak on terror support
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Not club cricket, says Kohli after umpiring error
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WhatsApp yet to comply with data storage norms
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Yes, there is corruption in judiciary: Madras HC
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Jet sending expensive expat pilots on furloughs
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No terror camp in India-cited areas: Pak on dossier
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We had courage to do surgical strikes: PM Modi
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Masood Azhar ban: How latest US move may put China in a tight corner
Chances are high that most of us will have a surgical procedure at some point during our lives. Estimates based on 2002 data in three states suggest Americans have a lifetime average of nine surgical procedures. In 2010 in the United States, there were an estimated 1.4 million inpatient procedures, ranging from childhood tonsillectomies, breast lumpectomies, and gallbladder removal to cataract surgeries, hernia repairs, and hip or knee replacements. And the rate of surgical procedures continues to rise. So it’s valuable to know what you can do to make safer surgery and a successful outcome more likely.
How do I choose my surgeon?
If you are having elective (non-emergency) surgery, such as a knee or hip replacement, you have a choice of surgeons. Your primary care physician, best friend, or physician acquaintance may recommend a surgeon. Even with a strong referral, though, it’s essential to ask questions. What do they like about that surgeon? Do they have any concerns you should be aware of?
When you meet with a surgeon, find out if he or she is board-certified. Board certification tells you that a doctor has gone beyond minimum licensing requirements to demonstrate expertise in their specialty. Ask how often the surgeon has done your procedure. Studies show that outcomes improve when a surgeon has more experience –– for example, in performing hip surgery.
Less obvious is whether you’ll have your procedure at a hospital that does a high or low volume of surgeries. Research suggests it’s safest to avoid having surgery at a hospital that does less than 10 per year of a given procedure. Outcomes are better for certain surgeries –– including orthopedic and cardiovascular procedures –– when performed in a hospital that does a high volume versus a low volume of surgeries. That’s because high-volume hospitals have processes, resources, and an experienced team that can lower complication rates and respond quickly if a complication does occur.
How do I choose my procedure?
Most often, your surgery will seem straightforward –– for example, you are having your gallbladder out. However, increasingly people are faced with several choices for a given surgery. For example:
- Traditional “open” surgeries are one option.
- Noninvasive approaches using laparoscopy are increasingly common. Laparoscopy is done using a small scope and tools that require a few small incisions, instead of the larger incision needed for open surgery.
- Sometimes there is a choice between laparoscopic robotic surgery — that means a robotic device helps the surgeon control the tools –– and standard laparoscopic surgery.
- Also, surgery like a hip replacement can be done with an anterior (front), lateral (side), or posterior (rear) approach. The newer anterior approach for hip replacement may not be how your surgeon was originally trained.
Ask which approach your surgeon plans to take, why, and what the risks and benefits are for this approach versus alternative options. Also ask about his or her experience with the chosen approach. Think about whether you prefer an older surgeon with deep experience using a traditional procedure or a more recently trained surgeon using new advances.
Prior to your surgery, you will be asked to sign an informed consent: one for your surgery, and another for your anesthesia. This is your time to ask questions about risks and alternatives, if you haven’t already done so.
If you feel inclined or your insurance requires this, get a second opinion. This is quite common. In fact, having a doctor discourage you from getting a second opinion is a red flag.
Are there steps I can take to help ensure safer surgery?
You can compare rates of surgical complications and infections at different hospitals on the Medicare website. You may also wish to check out your hospital’s patient satisfaction scores. These scores are also associated with higher surgical quality.
Although an infection after surgery is a common complication, you can take steps to protect yourself.
- You will likely be asked to bathe or shower before surgery with plain or antimicrobial soap. This reduces the likelihood of skin bacteria entering the incision.
- Not only do you want your surgical team to be clean and sterile, it’s also important that you, your visitors, and family members all wash hands rigorously. Be sure people do this when entering your room, after coughing, or before touching your skin following surgery.
- If you are having surgery after a long hospitalization or nursing home stay, you may be tested for colonization of a certain type of bacteria known as methicillin-resistant Staphylococcus aureus, or MRSA. If present, these bacteria can be eradicated prior to surgery.
Most importantly, always speak up if something doesn’t look or feel right. Ask your family members to do the same. You and your family members are valuable members of your safety team.
The post Safer Surgery: Steps you can take appeared first on Harvard Health Blog.
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Safer Surgery: Steps you can take
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Rahul promises to abolish angel tax for start-ups
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Congress blinded by anti-Modi sentiment:PM
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Bihar: Oppn alliance heading towards crisis; Congress bitter over raw deal
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Live: Karnataka CM joins protest over I-T raids
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Rescue yourselves from 'sarab': PM's jibe at oppn
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We will 'remonetise' what Modi 'demonetised': Rahul
from Times of India https://timesofindia.indiatimes.com/india/us-undermining-un-anti-terror-body-by-forcefully-moving-resolution-on-masood-azhar-in-unsc-china/articleshow/68612635.cms
US undermining UN by 'forcefully moving' resolution on Azhar: China
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North Korea hand in Pune's Cosmos Bank cyber heist: UNSC panel
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Live: India has made up its mind on who to elect in LS polls, PM says
Wednesday, 27 March 2019
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Pak says no terror camps on locations India shared
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The big hit in deep sky: In 3 minutes, India joins space 'super league'
from Times of India https://timesofindia.indiatimes.com/city/dehradun/beaten-to-death-by-seniors-dehradun-boarding-school-buries-body-of-12-yr-old-student-in-campus/articleshow/68603705.cms
School quietly buries 12-yr-old killed by seniors
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‘Air train’ plan to connect IGI set to take off
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Could there be any benefit associated with having migraine headaches? Most migraine patients would agree this is an odd question. Migraine is a common, inherited, lifelong, and often debilitating illness that impacts people most during their productive working and parenting years. It has been associated with a higher risk of vascular disorders such as stroke and heart attack, and psychiatric disorders like depression and anxiety. What could possibly be good about migraine?
Migraines may protect against type 2 diabetes
But maybe there is some good news. A recent study suggests that, at least in women, having a diagnosis of active migraine is somewhat protective against the development of type 2 diabetes. In this study, which followed nearly 75,000 women for 10 years, women with active migraine were 20% to 30% less likely to develop type 2 diabetes over the course of the study than women with no history of migraine. In addition, if the migraine condition improved and the headaches lessened, the chances of developing diabetes went up. This supports the notion that migraine is protective against developing diabetes, and this is not simply a chance association.
Headache specialists had long observed that their migraine patient populations did not develop diabetes as frequently as the general population, so this finding was not entirely unexpected. The reason for this relationship, though, remains unclear; after all, what could it be about having a headache that could make your blood sugar and insulin function improve? Looked at the other way around, one consideration could be that elevated blood sugar levels are somehow protective against developing a headache. Yet another explanation may have to do with CGRP, a protein molecule in the body that is active in both conditions and may be the factor that links them.
This was a large, well-conducted study. Two limitations were that it only studied women and that the population studied was a rather homogenous group of mostly white professionals. Nonetheless, experts feel that the findings can likely be generalized to other populations.
Migraines may protect against alcoholism
There is another beneficial effect of migraine: research has suggested that migraine sufferers are relatively protected against the development of alcoholism. This may be a more intuitive relationship than with diabetes, since many people with migraine report that they avoid alcohol because it can trigger headache.
Migraines may have offered an evolutionary advantage
The possible evolutionary advantages of migraine have also been studied. As a rule, conditions that impair the function of an individual should lead to poorer survival in the long run and eventual dying out of the trait. And yet, after millions of years, migraine survives and thrives.
Several evolutionary explanations have been cited. One is that migraine may have originally evolved as a protective alarm system against toxins entering the body. Avoiding the ingestion of toxic substances because they produce headache could result in improved health and evolutionary advantage, compared to individuals without headache who might overuse such substances and thus suffer undesirable consequences. The migraine that we know today may have developed as a result of overactivity or oversensitization of that evolutionarily important early warning system.
However small the practical and daily consequence to those who suffer its effects, migraine may in fact have one or more silver linings after all.
The post A silver lining for migraine sufferers? appeared first on Harvard Health Blog.
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A silver lining for migraine sufferers?
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Tuesday, 26 March 2019
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Racial differences have long been evident in prostate cancer statistics. In particular, African American men are diagnosed with prostate cancer more often than white men, and they’re also nearly twice as likely to die of the disease.
But new research also shows that African American men who receive the most advanced treatments for late-stage prostate cancer can live at least as long — or even longer — than their Caucasian counterparts.
Why is this the case? Scientists are searching for an explanation. “The fact that African American men have better survival is of huge research interest,” said Dr. Stephen Freedland, a urologist at Cedars-Sinai Medical Center in Los Angeles. “If we can figure this out, we’ll obtain key insights into the factors driving survival in late-stage prostate cancer. And that in turn will help spur better treatments for all men — regardless of race.”
Each year, about 160 per 100,000 African American men receive a prostate cancer diagnosis. That’s three times higher than the comparable figure for white American men, and it’s also higher than the number of black men diagnosed annually with prostate cancer in Africa. It’s possible that dietary or environmental factors — perhaps in combination with genetic susceptibilities — put African American men at greater risk in the United States. But African American men also tend to have less access to health care than white Americans, and many of them are diagnosed after their tumors have already begun to metastasize, or spread.
A surprising survival advantage
What the new research shows, however, is that survival advantages can favor African Americans who undergo treatment for advanced prostate cancer in clinical trials. One study pooled data from nine clinical trials, enrolling a combined 88,200 men with metastatic prostate cancer who were treated with a chemotherapy drug called docetaxel. The African American and white men had similar survival rates — 21 months and 21.2 months respectively. But after adjusting for factors such as age and prostate-specific antigen levels, the researchers found that African Americans were 20% less likely to have died during the course of those trials than their white counterparts.
Freedland co-authored another recent study showing that African Americans respond better to newer drugs that target testosterone, which is a hormone that drives prostate cancer to grow faster. Using data gathered by the Veterans Health Administration between 2013 and 2018, the researchers looked at how long African American and white men with metastatic prostate cancer lived after treatment with one of two drugs: abiraterone acetate or enzalutamide. They had access to records from nearly 3,000 men. The unpublished results, presented at a medical conference in February, showed that median survival among the African Americans lasted 30 months, compared to 26 months among their white counterparts. “So, the key takeaway is that if they get to advanced prostate cancer, and are treated equally in an equal access medical center, black men can have similar or even better outcomes,” Freedland said.
The data still need to be confirmed in additional research, Freedland emphasized. But in the meantime, the studies add to a growing body of evidence that’s changing how scientists look at racial differences in prostate cancer. Ideally, the research will reveal new biological insights into prostate cancer, and allow doctors to tailor treatments more effectively.
The post African American men respond better to treatments for advanced prostate cancer in clinical trials appeared first on Harvard Health Blog.
from Harvard Health Blog https://www.health.harvard.edu/blog/african-american-men-respond-better-to-treatments-for-advanced-prostate-cancer-in-clinical-trials-2019032616305
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African American men respond better to treatments for advanced prostate cancer in clinical trials
from Times of India https://timesofindia.indiatimes.com/elections/news/bjp-walks-the-no-dynasty-talk-denies-tickets-to-retirees-kin/articleshow/68588871.cms
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While pregnancy and a child’s birth are often depicted in pastel tones, many women struggle with depression during this time. Up to 14% of women are diagnosed with depression during pregnancy. Far more report having symptoms of depression during pregnancy and the first year after birth. Now new guidelines published by the US Preventive Services Task Force in the Journal of the American Medical Association provide the first-ever recommendations for preventing perinatal depression.
How can the new guidelines help?
Depression can be difficult during any period of life. Its main symptoms — a depressed or hopeless mood, a loss of interest and joy — can be accompanied by trouble sleeping, eating, and managing daily life. When depression occurs during pregnancy (perinatal) or up to 12 months after childbirth (postpartum), it can have a negative impact on the health of both the mother and the infant. For example, women with postpartum depression engage in fewer positive maternal behaviors, such as playing or praising, and more negative maternal behaviors, such as hurtful comments or harsh discipline. Children whose mothers had perinatal or postpartum depression are more likely to develop behavior problems and other psychiatric disorders.
The new guidelines recommend that health care providers discuss mental health with women during pregnancy and after birth, and screen women for depression. They can then refer women who report such symptoms, or have risk factors, to an appropriate mental health clinician. Simply raising the topic with a woman might help her feel more comfortable asking questions about depression and sharing her concerns.
Are there ways to prevent depression during pregnancy?
The Task Force reviewed a number of studies aimed at preventing depression in pregnant women. It identified two counseling interventions as recommended practices: cognitive behavioral therapy and interpersonal therapy. Both can effectively prevent perinatal depression.
Cognitive behavioral therapy, or CBT, helps people identify and change negative and incorrect thoughts. It helps people develop alternate, and more accurate, ways of viewing themselves and life events. For example, you might have broad, global, negative views of your ability to parent (“I am a terrible parent.”). Therapy focuses on identifying these thoughts, challenging the errors in them, and developing more balanced thoughts. The behavioral component of CBT includes increasing positive activities, such as social interactions and pleasant events.
Interpersonal therapy focuses on helping people resolve interpersonal conflicts and navigate role transitions, such as becoming a mother for the first time. It also teaches people how to increase effective communication with others.
The Task Force found limited or mixed evidence for other approaches to preventing depression in pregnant women, including taking dietary supplements and engaging in physical activity.
What else is important for preventing depression during pregnancy?
Further, the Task Force identified a number of risk factors that make women more vulnerable to perinatal depression. These factors include having a history of depression, experiencing abuse, having an unplanned or unwanted pregnancy, or complications during pregnancy. Other possible risk factors are stressful life events, diabetes, low socioeconomic status, lack of financial or social support, and teen parenthood. Women who have these risk factors may wish to consider counseling during pregnancy and after childbirth. Counseling can be a source of support and a way to prevent, or cope with, depression.
The Task Force recommended further efforts to develop new ways to screen women for depression and prevent depression.
What if you’re experiencing depression?
If you are experiencing symptoms of depression, it is important to talk to your health care provider about treatment options. Your provider can refer you to mental health professionals who have experience working with women during pregnancy or after a birth. Encourage friends and family who are experiencing depression to seek help.
In addition to seeking help for symptoms of depression, if you or a friend of yours is thinking about harming themselves, please call the Suicide Prevention Hotline at 800-273-8255 (TALK), or go to the closest emergency room for help.
Editor’s note
In March 2019, the FDA approved the first treatment for moderate to severe postpartum depression. Brexanolone (Zulresso) is given intravenously over a 60-hour period. During this time, women must be monitored at a certified health care facility. While the medicine can work quickly to ease depression (within 48 hours), it is not effective for everyone.
The post Preventing depression in pregnancy: New guidelines appeared first on Harvard Health Blog.
from Harvard Health Blog https://www.health.harvard.edu/blog/preventing-depression-in-pregnancy-new-guidelines-2019032616263
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Preventing depression in pregnancy: New guidelines
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In a first, scientists grow humanised kidney: Full report
A study published in the scientific journal Cell Stem Cell has depicted growing humanised kidney inside pigs. Pigs are highly attractive tar...