Thursday, 30 April 2020
from Times of India https://timesofindia.indiatimes.com/india/relief-for-maharashtra-cm-ec-to-hold-council-polls-before-may-27/articleshow/75485504.cms
Maha: EC to hold council polls before May 27
from Times of India https://timesofindia.indiatimes.com/business/india-business/lockdown-maruti-sells-zero-units-in-domestic-market-in-april/articleshow/75484457.cms
Maruti sells zero units in domestic market in April
from Times of India https://timesofindia.indiatimes.com/india/breaking-news-live-updates-01-05-2020/liveblog/75483373.cms
Live: EC allows to hold elections to MLC
from Times of India https://timesofindia.indiatimes.com/city/bengaluru/karnataka-plans-to-open-malls-liquor-outlets-from-may-4/articleshow/75482674.cms
K'taka to open malls, liquor outlets from May 4
from Times of India https://timesofindia.indiatimes.com/india/states-face-daunting-task-of-evacuating-millions-of-migrants/articleshow/75481602.cms
States face daunting task of evacuating millions of migrants
As the COVID-19 pandemic continues, new challenges arise each day for people across the world. Some of these challenges particularly affect the LGBTQ+ community. This unique time calls for LGBTQ+-specific resources and new ways to connect and cope.
Minority stress in the LGBTQ+ community
Unrelated to COVID-19, this community faces minority stress based on anti-LGBTQ+ stigma that is harmful for their health and well-being (see key articles here and here). Those among us who are also racial/ethnic minorities, people with disabilities, immigrants, and people with low income may experience compounded minority stress at the intersections of these identities. For example, a person who is Black and bisexual may experience minority stress differently from someone who is White and gay, even though both of these people are LGBTQ+. LGBTQ+ Asian Americans may be experiencing even greater minority stress, due to increased discrimination against Asian Americans because the first COVID-19 outbreak was in China.
Research has shown that minority stress harms the mental and physical health of LGBTQ+ people (see here and here). It contributes to higher risk for a number of health problems, including anxiety and depression, which may worsen due to the stress of COVID-19.
New forms of stress for the LGBTQ+ community during the COVID-19 pandemic
Loss of work and income. Compared with non-LGBTQ+ people, LGBTQ+ people are more likely to have lower income and to have jobs that do not allow for working from home, such as retail stores and the service industry. Therefore, LGBTQ+ people may be more likely to experience food or housing insecurity during this time.
School closures. School closures may be especially challenging for the LGBTQ+ community. Many LGBTQ+ youth and young adults have experienced rejection from their family of origin. With schools closed and colleges and universities now online, LGBTQ+ youth and young adults with unsupportive families may now be home with those families full-time, or must find another place to live if they have been kicked out. Some LGBTQ+ youth and young adults who were “out” as LGBTQ+ at school and with peers, but not with their family, may now have to choose whether to hide their identities while they are at home.
Reduced access to care. During the COVID-19 pandemic, many forms of care that are considered nonessential have been delayed, with unique effects on the LGBTQ+ community. Transgender and nonbinary people may have trouble accessing gender-affirming care because hormones and surgeries may be considered nonessential. However, research suggests that access to gender-affirming care, such as hormonal treatments and surgery, is essential to the health and well-being of transgender and nonbinary individuals.
For LGBTQ+ people who are building families, access to fertility clinics is essential. However, many clinics are now delaying fertility treatments, which also delays family building for LGBTQ+ families.
Worries about seeking care for COVID-19 symptoms. Many LGBTQ+ people have had negative experiences with healthcare in the past, especially transgender and nonbinary people who have experienced discrimination related to their gender identity or gender expression. Thus, some LGBTQ+ people may need encouragement to seek care if they have COVID-19 symptoms, such as fever, cough, and fatigue.
Reduced access to legal protections. Even during this COVID-19 crisis, laws that restrict rights for the LGBTQ+ community continue to be proposed. In addition, LGBTQ+ people may be unable to access existing legal protections because of COVID-19-related closures. LGBTQ+ people with housing insecurity may be unable to access legal help to contest evictions because many lawyers are not currently taking new clients. LGBTQ+ families may lose access to critical legal protections related to co-parent adoption while family courts are closed. At a time when so many have become sick from COVID-19, ensuring the legal rights of a nongestational parent in a same-sex couple if the gestational parent becomes ill is more important than ever.
Coping with stress and loss of support
Some research finds that LGBTQ+ people are more likely to use stress-relief strategies that may be harmful, such as using tobacco or vaping and other substance use. So it’s possible that LGBTQ+ people may increase their use of unhealthy substances to cope with the stress of daily life during a pandemic.
As freedom of movement is restricted to curb the spread of COVID-19 through physical (“social”) distancing, many helpful coping strategies, such as meeting friends and spending time gathering in the community, are not an option. LGBTQ+ people who already feel isolated due to family rejection or the stigma of being LGBTQ+ may feel even more isolated with physical distancing and other restrictions on freedom of movement.
Helpful resources for the LGBTQ+ community
Many LGBTQ+ people have developed robust online communities of “chosen family” who continue to provide support and affirmation — resources which you may find helpful. Additionally, some organizations may be able to help you find local resources.
If you’re seeking support and mental health resources:
- Family Acceptance Project Support for LGBTQ+ youth and their families
- Gender Spectrum Resources for challenging times, including online support groups for transgender and nonbinary youth and their families
- LGBTQ+ mental health and substance use information and resources from the Substance Use and Mental Health Services Administration (SAMHSA)
- LGBT National Help Center Support and resources for LGBTQ+ people of all ages, including hotlines, online chat, and connections to local resources
- SAGE LGBT Elder Hotline (877-360-5428) Support for LGBTQ+ seniors
- The Neighborhood: A Virtual Hub for LGBTQ+ Families from Family Equality Online: events and support groups for LGBTQ+ prospective and current parents
- The Trevor Project (866-488-7386) Support for LGBTQ+ young people, including a confidential hotline, online chat, and text messaging
- Trans Lifeline (877-565-8860) Peer-to-peer support for the transgender community
If you’re experiencing financial insecurity:
- Mutual aid and emergency funds for LGBTQ+ individuals, compiled by the National Center for Transgender Equality
- Rapid response and emergency funds for LGBTQ+ individuals and organizations, compiled by Funders for LGBTQ Issues
If you’re struggling with access to health care or legal protections:
- Resources for LGBTQ patients GLMA Health Professionals Advancing LGBTQ Equality
- LGBTQ+ legal rights and resources GLAD Legal Advocates and Defenders
- Transgender rights and resources the Transgender Legal Defense & Education Fund
For more information on coronavirus and COVID-19, see the Harvard Health Publishing Coronavirus Resource Center and podcasts.
The post COVID-19 and the LGBTQ+ community: Rising to unique challenges appeared first on Harvard Health Blog.
from Harvard Health Blog https://www.health.harvard.edu/blog/covid-19-and-the-lgbtq-community-rising-to-unique-challenges-2020043019721
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COVID-19 and the LGBTQ+ community: Rising to unique challenges
from Times of India https://timesofindia.indiatimes.com/india/covid-19-states-prepare-migrant-movement-plans-centre-says-recovery-rate-up-at-over-25/articleshow/75477872.cms
States prepare migrant movement plans; Centre says recovery rate 25%
from Times of India https://timesofindia.indiatimes.com/india/maha-governor-write-to-eci-seeks-polls-for-nine-council-seats/articleshow/75476435.cms
Declare polls for 9 Council seats: Maha gov to EC
from Times of India https://timesofindia.indiatimes.com/india/allow-free-movement-of-trucks-goods-to-maintain-supply-chain-mha-tells-states/articleshow/75474515.cms
Allow free movement of trucks: MHA to states
Non-alcoholic fatty liver disease is the most common cause of liver disease in the United States, and is estimated to affect up to a quarter of adults in the world. It is defined by excess fat accumulating in the liver and usually occurs in people with obesity, high blood sugars (diabetes), abnormal cholesterol or triglyceride levels, or high blood pressure. These disorders often run together and as a group are called metabolic syndrome. The “non-alcoholic” part of “non-alcoholic fatty liver disease” is important to distinguish it from alcohol-related liver disease, which can also cause excess liver fat.
How fat can damage the liver
In some people, the excess fat sits in the liver but may not cause any liver damage. However, in about one in 20 people, excess liver fat triggers chronic liver inflammation. This condition is called non-alcoholic steatohepatitis or NASH (“steato-“ means relating to fat and “hepatitis” means liver inflammation).
As with other liver disease, such as viral hepatitis or alcohol-related liver disease, chronic inflammation can cause ongoing damage, which leads to liver scarring known as fibrosis. Severe fibrosis is called cirrhosis regardless of the cause. People with cirrhosis are at risk for liver failure and liver cancer, and may need liver transplantation.
Diagnosing fatty liver
The key to preventing complications of NASH is to catch it early and treat it before the liver has sustained significant damage. Early diagnosis is tricky; usually people have no symptoms from their liver disease. If you have been diagnosed with any of the components of metabolic syndrome, you should talk to your doctor about your risk of having NASH.
The most accurate way to diagnose NASH is by liver biopsy. But blood tests and imaging tests can be used to determine who might be at low risk for NASH to avoid unnecessary liver biopsies. A useful, noninvasive test for some people is liver elastography, a special kind of ultrasound that estimates how much scarring there is in the liver. Elastography can help sort out who might benefit from further testing by liver biopsy. Regardless of whether NASH is present, exercising and eating a healthy diet can go a long way in treating metabolic syndrome and preventing complications down the road.
Weight loss is key to preventing complications of fatty liver
For people who are overweight or have obesity, the best treatment for NASH is weight loss. A landmark study showed that losing 10% of one’s body weight can reduce liver fat, resolve inflammation, and potentially improve scarring. More recently, in a meta-analysis published in JAMA Internal Medicine, researchers combined data from 22 studies that randomized patients to a weight loss intervention or a control arm (no or lower-intensity weight-loss intervention), to take a more thorough look at the effect of weight loss on non-alcoholic fatty liver disease.
That meta-analysis and other studies confirmed that weight loss by behavioral programs, medications, or weight-loss surgery can successfully treat NASH. Diet and exercise are the first line of treatment. At least 150 minutes of heart-pumping activity is recommended. While it’s not clear which diet is best, those that emphasize vegetables and whole foods, such as the Mediterranean diet, are good options. Regardless of the exact plan, lifestyle changes should be sustainable, and it’s usually best to lose weight slowly over time.
If sufficient weight loss is not attainable with these steps, weight loss surgery, such as gastric sleeve or gastric bypass, can be considered. There are currently no FDA-approved medications specifically for NASH, but medications that promote weight loss may be helpful. For certain people without diabetes, vitamin E can help treat NASH. For those with diabetes, certain medications that improve blood sugar, such as the thiazolidinedione drug pioglitazone (Actos) and the incretin mimetic drug liraglutide (Saxenda), may also have beneficial effects on the liver. Any decisions regarding medications for NASH, including the use of vitamin E, should be made in consultation with your doctor.
Individuals with NASH must also protect the liver from any other causes of liver inflammation. This means abstaining from alcohol and making sure you are vaccinated against the hepatitis A and hepatitis B viruses. Finally, anyone with NASH should also identify and treat individual components of metabolic syndrome they may have, in order to reduce the risk of heart disease and strokes.
Awareness of fatty liver may help head off problems down the road
Non-alcoholic liver disease is becoming more prevalent as obesity becomes more common. It is also underdiagnosed, since it usually causes no symptoms. But increased awareness can lead to early diagnosis and prevention of serious problems down the road. Fortunately, active research is ongoing to define how to best identify people who are at risk and to develop new medications to treat NASH.
The post Weight loss can help head off lasting damage caused by fatty liver appeared first on Harvard Health Blog.
from Harvard Health Blog https://www.health.harvard.edu/blog/weight-loss-can-help-head-off-lasting-damage-caused-by-fatty-liver-2020043019664
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Weight loss can help head off lasting damage caused by fatty liver
from Times of India https://timesofindia.indiatimes.com/world/us/covid-19-news-media-outlets-have-been-ravaged-by-the-pandemic/articleshow/75474620.cms
News media outlets have been ravaged by Covid
from Times of India https://timesofindia.indiatimes.com/india/pm-modi-discusses-strategies-to-promote-investment-boost-economy/articleshow/75472235.cms
PM Modi discusses strategies to boost economy
from Times of India https://timesofindia.indiatimes.com/entertainment/hindi/bollywood/news/rishi-kapoor-cremated-at-chandawadi-alia-bhatt-saif-ali-khan-kareena-kapoor-abhishek-bachchan-attend-his-last-rites/articleshow/75470463.cms
Rishi Kapoor cremated; Alia, Saif, Kareena, Abhishek attend last rites
from Times of India https://timesofindia.indiatimes.com/entertainment/hindi/bollywood/news/rishi-kapoors-daughter-riddhima-kapoor-sahni-shares-throwback-pictures-of-the-actor-writes-wish-i-could-be-there-to-say-goodbye-to-you/articleshow/75470647.cms
Wish I could be there with you: Rishi's daughter
from Times of India https://timesofindia.indiatimes.com/india/sc-refuses-to-stay-govts-central-vista-redevelopment-project/articleshow/75467935.cms
SC refuses to stay govt's Central Vista project
from Times of India https://timesofindia.indiatimes.com/entertainment/hindi/bollywood/news/riddhima-kapoor-shares-a-selfie-with-father-rishi-kapoor-says-rip-my-strongest-warrior-i-will-miss-you-everyday/articleshow/75468339.cms
'RIP my strongest warrior': Rishi's daughter
from Times of India https://timesofindia.indiatimes.com/entertainment/hindi/bollywood/news/heres-how-alia-bhatt-became-ranbir-kapoors-pillar-of-strength-in-the-last-few-weeks/articleshow/75465429.cms
Rishi's death: How Alia became Ranbir's strength
from Times of India https://timesofindia.indiatimes.com/india/pm-modis-popularity-soars-amid-indias-covid-fight/articleshow/75466935.cms
Modi's popularity soars amid India's Covid fight
from Times of India https://timesofindia.indiatimes.com/india/number-of-non-covid-deaths-emergency-cases-has-dropped/articleshow/75461794.cms
Why non-Covid deaths has dropped in India
from Times of India https://timesofindia.indiatimes.com/city/meerut/saharanpur-wakes-up-to-himalayas-visible-from-town-after-30-years-as-aqi-dips-below-50/articleshow/75465589.cms
Saharanpur wakes up to Himalayas
Wednesday, 29 April 2020
from Times of India https://timesofindia.indiatimes.com/entertainment/hindi/bollywood/news/rishi-kapoor-passes-away-amitabh-bachchan-akshay-kumar-taapsee-pannu-and-others-mourn-the-sad-demise-of-bollywoods-legendary-actor/articleshow/75464147.cms
Bollywood mourns demise of legend Rishi Kapoor
from Times of India https://photogallery.indiatimes.com/celebs/bollywood/rare-and-unseen-pictures-of-bollywood-actor-rishi-kapoor-who-passed-away-at-67/Rare-and-unseen-pictures-of-Bollywood-actor-Rishi-Kapoor/articleshow/75463612.cms
Rare pics: Rishi Kapoor passes away
from Times of India https://timesofindia.indiatimes.com/india/coronavirus-in-india-live-updates-indias-covid-19-cases-climbed-to-33050/liveblog/75461685.cms
Live: Total Corona cases in India rises to 33,050
from Times of India https://timesofindia.indiatimes.com/business/india-business/raghuram-rajan-says-focus-of-the-government-should-be-on-starting-peoples-lives-first-key-points/articleshow/75463529.cms
Rahul Gandhi-Rajan interaction: Key points
from Times of India https://timesofindia.indiatimes.com/entertainment/hindi/bollywood/news/rishi-kapoor-passes-away-at-67-after-a-long-battle-with-cancer/articleshow/75463868.cms
Rishi Kapoor passes away at 67 after a long battle with cancer
from Times of India https://timesofindia.indiatimes.com/india/states-start-plasma-therapy-trials-hcq-administration-in-war-covid/articleshow/75461803.cms
States start plasma therapy trials, HCQ administration in War Covid
from Times of India https://timesofindia.indiatimes.com/sports/cricket/news/coaches-have-had-to-become-creative-rahul-dravid/articleshow/75462499.cms
Coaches have had to become creative: Dravid
from Times of India https://timesofindia.indiatimes.com/entertainment/hindi/bollywood/news/irrfan-khan-passes-away-at-53-suffers-complications-due-to-colon-infection/articleshow/75455639.cms
Irrfan passes away at 53 due to colon infection
from Times of India https://timesofindia.indiatimes.com/india/uddhav-speaks-to-pm-modi-as-he-awaits-governors-decision/articleshow/75454257.cms
Attempts to create instability, Uddhav tells PM
from Times of India https://timesofindia.indiatimes.com/home/education/news/ugc-issues-new-calendar-for-universities-2020-21-session-to-begin-from-aug-1/articleshow/75453706.cms
UGC issues univ calendar; new session from Aug 1
Perhaps you’ve grown as weary as I have of repeated arthritis ads. They appear in frequent rotation on television, online, and in magazines, promoting Enbrel, Humira, Otezla, Xeljanz, and others.
If you’ve actually read or listened to these ads, you might have felt perplexed at certain points. Here’s a quick rundown on what they’re saying — and not saying — in one of those ads.
“The clock is ticking”
Part 1: A teakettle whistles on the stove and a disembodied voice speaks as this ad for Humira opens. “This is your wakeup call. If you have moderate to severe rheumatoid arthritis, month after month the clock is ticking on irreversible joint damage. Ongoing pain and stiffness are signs of joint erosion.” Three people are shown starting their day in pain: one rubs his knee and grimaces, another has a sore shoulder, and the third, sore hands. Their suffering is clear, and you hear ticking in the background as a digital clock clicks forward one minute.
Part 2: “Humira can help stop the clock.” A garage door opens and out comes the man with the achy knee, now smiling and comfortably walking out into the sunshine as the music swells. “Prescribed for 15 years, Humira targets and blocks a source of inflammation that contributes to joint pain and irreversible damage.”
Part 3: The long list of side effects is voiced while happy scenes and beautiful music distract you: an adorable dog hikes with its once-achy-kneed owner; a young mother drops off her kids with a beaming grandma who previously was wringing her sore hands. “Humira can lower your ability to fight infection. Serious and fatal infections including tuberculosis and cancers, including lymphoma, have happened, as have blood, liver, and nervous system problems, serious allergic reactions, and new or worsening heart failure. Tell your doctor if you’ve been to areas where certain fungal infections are common, and if you’ve had tuberculosis, hepatitis B, are prone to infections, or have flulike symptoms or sores. Don’t start Humira if you have an infection.”
Part 4: The big finish is short and to the point: “Help stop the clock on irreversible joint damage. Talk to your rheumatologist.”
What did the ad get right?
Let’s start with several accurate points:
- The prolonged morning stiffness depicted at the start is a typical symptom of rheumatoid arthritis (RA). It’s so characteristic that it helps doctors make the diagnosis.
- Humira is a brand name of adalimumab, a treatment for rheumatoid arthritis and related conditions. It’s often highly effective and has a good safety profile, despite the long disclaimer about side effects.
- The drug targets inflammation. It does this by blocking tumor necrosis factor (TNF), a substance directly involved in rheumatoid arthritis inflammation. Anti-TNF drugs were first approved by the FDA for rheumatoid arthritis more than 20 years ago. They have revolutionized treatment for this disease.
- An active lifestyle is a reality for many people with rheumatoid arthritis who begin effective treatment soon after symptoms begin. The potential for improvement is often underestimated, perhaps because it wasn’t long ago that doctors had few effective options to treat rheumatoid arthritis. Fortunately, that has changed.
Now, about the rest of the ad
- Ongoing pain and stiffness are not specific signs of joint erosion. They are symptoms of joint inflammation, which may, over time, lead to erosions. However, not everyone with RA experiences joint erosions, and it generally takes many weeks or months for erosions to develop. Showing a clock with minutes ticking by implies more urgency than is accurate.
- The word “irreversible” is stated three times in this 60-second ad. While it’s true that joint damage related to RA generally does not heal, some people have minimal or no damage, especially when taking effective treatment. The implication that permanent joint damage is inevitable seems overly dramatic to me, and perhaps alarmist.
- The FDA requires that long disclaimer. While it lists the most important risks and side effects of the drug, some of its equivocal language is chosen carefully: “Serious and fatal infections… and cancers… have happened.” Were these problems caused by adalimumab? Or were they unrelated? Or do they just not know? Generally, the safety profile of anti-TNF drugs is considered good. The most recent studies suggest that there is no significant increased risk of cancer, except for skin cancers.
- I would bet that the average person seeing this ad has no idea if they’ve been in places where “certain fungal infections are common” — or what that even means! In fact, it refers to certain infections that can become silent in the body, but re-activate in people taking adalimumab. This includes histoplasmosis (Midwest of the US), Coccidioides (southwestern US), and blastomycosis (Ohio and Mississippi River Valleys and the Great Lakes).
What’s left unsaid?
The ad never mentions some important information about adalimumab:
- It’s expensive. While insurance may cover most or all of the cost, the price of adalimumab can run about $40,000/year.
- It’s given by injection under the skin (a bit like insulin injections for people with diabetes), usually every two weeks.
- Humira is only approved — and likely to work — for a few arthritic conditions, including RA. It’s not for osteoarthritis, the most common type of arthritis, an age-related, degenerative joint disease.
- Four other medications work in a similar way, with similar effectiveness and similar cost, side effects, and risks. Additionally, a host of other medications unrelated to TNF inhibition are also just as effective.
The bottom line
As drug ads go, those for arthritis in general and adalimumab in particular are not the worst I’ve seen. But they can be misleading, perplexing, and incomplete. Of course, the main purpose of these ads is to sell drugs, not to provide a complete and balanced review of treatment options for RA. You’ll need to ask your doctor for that.
Follow me on Twitter @RobShmerling
The post Harvard Health AdWatch: An arthritis ad in 4 parts appeared first on Harvard Health Blog.
from Harvard Health Blog https://www.health.harvard.edu/blog/harvard-health-adwatch-an-arthritis-ad-in-4-parts-2020042919703
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Harvard Health AdWatch: An arthritis ad in 4 parts
from Times of India https://timesofindia.indiatimes.com/india/govt-allows-movement-of-stranded-people-with-conditions/articleshow/75453755.cms
MHA allows inter-state travel of stranded people
from Times of India https://timesofindia.indiatimes.com/india/death-toll-due-to-covid-19-now-at-1008-cases-climb-to-31787-health-ministry/articleshow/75452106.cms
1,008 Covid deaths, 31,787 cases in India: Govt
from Times of India https://timesofindia.indiatimes.com/india/interstate-travel-of-stranded-people-here-are-the-mha-guidelines/articleshow/75451918.cms
Interstate travel of stranded people: Guidelines
from Times of India https://timesofindia.indiatimes.com/world/us/top-us-health-advisor-dr-fauci-backed-controversial-wuhan-lab-for-risky-coronavirus-research-report/articleshow/75449844.cms
'Fauci backed China lab for risky corona research'
from Times of India https://timesofindia.indiatimes.com/entertainment/hindi/bollywood/news/irrfan-khans-funeral-takes-place-amidst-lockdown-under-heavy-police-deployment/articleshow/75447355.cms
'He was strong in his fight': Actor Irrfan Khan laid to rest in Mumbai
from Times of India https://timesofindia.indiatimes.com/sports/cricket/news/ms-dhoni-greatest-finisher-i-have-seen-says-mike-hussey/articleshow/75449604.cms
Dhoni greatest finisher I have seen: Mike Hussey
from Times of India https://timesofindia.indiatimes.com/india/coronavirus-india-updates-live-indias-covid-19-cases-rises-to-31332-cases-death-toll-at-1007/liveblog/75418221.cms
Live: Kerala to issue ordinance for staff pay cut
from Times of India https://timesofindia.indiatimes.com/india/day-36-of-coronavirus-lockdown-ground-report-from-indian-cities/articleshow/75444823.cms
Ground report from Indian cities
from Times of India https://timesofindia.indiatimes.com/sports/cricket/news/kamran-akmal-wants-umar-to-learn-from-sachin-tendulkar-ms-dhoni-virat-kohli/articleshow/75445484.cms
'Umar should learn from Sachin, Dhoni, Kohli'
from Times of India https://timesofindia.indiatimes.com/business/international-business/over-2-lakh-h-1b-workers-could-lose-legal-status-by-june/articleshow/75444330.cms
Over 2 lakh H-1B workers could lose legal status
Tuesday, 28 April 2020
from Times of India https://timesofindia.indiatimes.com/entertainment/hindi/bollywood/news/irrfan-khan-passes-away-at-53-battling-colon-infection/articleshow/75444038.cms
Actor Irrfan Khan passes away at 53, battling colon infection
from Times of India https://timesofindia.indiatimes.com/india/85-correlation-between-temperature-rise-cut-in-virus-spread-study/articleshow/75439996.cms
85% correlation between temp rise & cut in virus spread: Study
from Times of India https://timesofindia.indiatimes.com/world/rest-of-world/kim-jong-uns-uncle-suddenly-relevant-after-four-decades-abroad/articleshow/75442648.cms
Kim Jong-un’s uncle relevant after 40 yrs abroad
from Times of India https://timesofindia.indiatimes.com/city/thiruvananthapuram/norka-registrations-touch-2-76-lakh/articleshow/75441237.cms
Kerala braces for 3 lakh expats waiting to return
from Times of India https://timesofindia.indiatimes.com/business/india-business/7-4-lakh-pull-out-additional-rs-2400cr-from-epf-in-1-month/articleshow/75439934.cms
7.4L pull out additional Rs 2,400cr from EPF
from Times of India https://timesofindia.indiatimes.com/city/bengaluru/graded-lockdown-exit-in-22-districts-from-today-relief-for-bengaluru-in-may/articleshow/75440201.cms
K'taka: Graded lockdown exit in 22 districts; relief for B'luru in May?
from Times of India https://timesofindia.indiatimes.com/india/300-districts-covid-free-another-300-have-very-few-cases-govt/articleshow/75440006.cms
300 districts, 5 states and UTs are still Covid-free, govt says
from Times of India https://timesofindia.indiatimes.com/world/us/as-us-covid-19-cases-hit-1m-many-americans-opt-to-stay-on-in-india/articleshow/75440837.cms
Corona: Many Americans opt to stay put in India
from Times of India https://timesofindia.indiatimes.com/sports/more-sports/others/live-camera-traction-how-top-sports-stars-maintain-good-cheer-and-connect-with-fans/articleshow/75440738.cms
Sports stars devise way to maintain good cheer
from Times of India https://timesofindia.indiatimes.com/sports/boxing/india-lose-hosting-rights-of-2021-mens-world-boxing-championships/articleshow/75433498.cms
India lose hosting rights of men's boxing worlds
Two headlines caught my eye recently:
The relationship between chronic diseases and number of sexual partners: an exploratory analysis
and
Study warns more sex might mean higher likelihood for cancer
It may be hard to believe, but both of these refer to same medical research. I’m not sure which one I like better. The first one is the actual title of the research, which provides no information about its findings. The second one is a newspaper headline. It cuts right to the chase about the study’s main findings. While it’s much more specific — and alarming — it is also misleading.
Is there a link between the number of sexual partners and cancer?
The study investigating this possibility was published BMJ Sexual & Reproductive Health. It enrolled about 2,500 men and 3,200 women who were 50 or older (average age 64). Each person was surveyed about the total number of sexual partners they’d had over the course of their lives. This information was compared with a number of medical conditions they’d developed, including cancer, heart disease, and stroke.
The study demonstrated that
- Men who reported 10 or more sexual partners in their life were nearly 70% more likely to have developed cancer when compared with those reporting 0 or 1 lifetime sexual partners.
- For women, the findings were even more dramatic: women who reported 10 or more sexual partners in their life were nearly 91% more likely to have developed cancer when compared with those reporting 0 or 1 lifetime sexual partners.
Men were more likely than women to report having at least 10 partners (22% of men vs. 8% of women) while women were more likely to have fewer partners (41% of women and 28.5% of men reporting having had 0 to 1 partners).
It’s worth noting this study was performed in England with health information initially collected in the late 1990s. The results could have been different if researchers had assessed risk of a different population or at a different point in time. In addition, self-reporting was relied upon to assess sexual behavior, and it’s possible the reported number of sexual partners and other health behaviors were not accurate.
Does this mean having sex leads to cancer?
The answer is almost surely no.
That’s because this type of study cannot assess whether sex causes cancer. It can only determine whether there is a correlation between the two. Also, we already know of ways that sexual behavior can indirectly affect cancer risk without actually causing cancer, especially through sexually transmitted infections. Some of the strongest connections are for:
- human papilloma virus (HPV), which increases the risk of cancers of the cervix, mouth, penis, and anus
- human immunodeficiency virus (HIV) infection, which increases the risk of cancers such as Kaposi’s sarcoma and lymphoma
- hepatitis B and hepatitis C infection, which have been linked to liver cancer
- gonorrhea, which increases the risk of prostate cancer (particularly among African American men).
In addition, people with more sexual partners tended to smoke more and drink more alcohol. These factors could, themselves, increase the risk of cancer. So, certain factors — in these cases, infections, smoking, and drinking — could have an impact on cancer risk, rather than having sex or the number of sexual partners.
While future research could find previously unidentified risks in having a higher number of sexual partners, we already know enough to explain the connection.
The bottom line
While it may be tempting to conclude from this new research that limiting the number of sexual partners you have will lower your risk of cancer, I think that would be a misinterpretation of the data. The better take-home message would be to take precautions to avoid sexually transmitted diseases and pursue other proven strategies to lower your cancer risk, including stopping smoking and limiting alcohol.
Follow me on Twitter @RobShmerling
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More sexual partners, more cancer?
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Treatments for prostate cancer are always evolving, and now research is pointing to new ways of treating a cancer that has just begun to spread, or metastasize, after initial surgery or radiation. Doctors usually give hormonal therapies in these cases to block testosterone, which is a hormone that makes the cancer grow faster. But newer evidence shows that treating the metastatic tumors directly with radiation can produce better results.
In March, researchers published the latest study that supports this approach. Based at Johns Hopkins University School of Medicine in Baltimore, the team used a method for delivering powerful beams of high-dose radiation to very small cancers in the body. This approach is called stereotactic ablative radiotherapy (SABR), and it can spare healthy tissues with remarkable precision. Doctors map out where to pinpoint the radiation in advance by putting patients into a computed tomography (CT) scanner that takes x-rays of the body from many different angles.
During their study, the Johns Hopkins team recruited 54 men with three or fewer metastatic tumors. All the men had already undergone initial treatment for cancer while it was still in the prostate, and some had also been treated with hormonal therapy, though not within six months of being enrolled for the research. The men were 68 years old on average, and they were each randomly assigned to one of two groups: A third of the men were placed in an observation (control) group, meaning they received no additional treatment until the study was over. The rest were given SABR at a rate of one to five treatments per tumor over a period of about a week.
Then the men were followed for six months and monitored for changes such as PSA increases, tumor growth, worsening symptoms, or how many men wound up on hormonal therapy.
What the results showed
Results showed that the SABR-treated men fared better in all respects. Overall, 19% of those who got the targeted radiation had their cancers progress, compared to 61% of men in the control group. Taken together, the findings support a view that all detectable lesions should be removed, if feasible, to maximize the odds “of a cancer cure,” according to the authors of an editorial accompanying the published paper.
What makes SABR effective for treating early-stage metastases? Scientists are trying to find out. The investigators behind this study speculated that irradiating visible traces of cancer might block signals that feed the growth of even smaller tumors that are still too small to see. It’s also possible that radiation induces a sort of vaccinating effect, which prompts the immune system to attack other tumor cells.
Meanwhile, SABR could soon benefit from an ability to flag even smaller tumors for treatment. A new type of imaging scan called PMSA-targeted positron emissions tomography (PET) was tested in the study, and it found very small tumors that CT scanning had missed.
Dr. Marc Garnick, Gorman Brothers Professor of Medicine at Harvard Medical School and Beth Israel Deaconess Medical Center, and editor in chief of HarvardProstateKnowledge.org, says the whole concept of treating metastatic prostate cancer “is undergoing re-evaluation.” He added, “The findings in this case need to be supported with a larger study. However, this research provides more evidence that for patients with less extensive metastasis, SABR treatments can significantly delay systemic therapies such as chemotherapy or hormonal treatment.”
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New radiation therapies keep advanced prostate cancer in check
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If you are staying safe at home with a roommate or family member, try this partner workout led by pro runners Aisha Praught-Leer and Will Leer.
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Partner Bodyweight Workout with Pro Runners
Try this partner workout with Great Britain Track & Field athletes Shannon Hylton and Cheriece Hylton.
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Partner Home Workout with The Hylton Twins
Performance nutritionist Dr. Marc Bubbs provides tips on how to snack less.
The post How to Snack Less appeared first on Under Armour.
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How to Snack Less
Pro heptathlete Georgia Ellenwood takes you through an at-home bodyweight workout.
For more inspiration, check out “Workout Routines” in the app to discover and log a wide variety of routines by Under Armour Performance Specialists. Or build your own routine with exercises that fit your goals.
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Runner’s Bodyweight Workout With Georgia Ellenwood
Fire up the legs in this home workout with pro runner Rachel Schneider.
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Runner’s Leg Workout with Rachel Schneider
Performance nutritionist Dr. Marc Bubbs explores sources of vitamin D: sun exposure, supplementation and food.
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Sources of Vitamin D
Take 10 minutes to sweat with health & fitness coach Emily Ricketts’ at-home AMRAP workout.
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10 Minute AMRAP with Emily Ricketts
Sport psychologist Dr. Michael Gervais proposes 3 C’s we can practice to become more resilient.
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A study published in the scientific journal Cell Stem Cell has depicted growing humanised kidney inside pigs. Pigs are highly attractive tar...